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Fuchs’ endothelial dystrophy is a disorder in which the corneal endothelium becomes progressively weak, leading to corneal decompensation and decreased vision. Because Fuchs’ worsens with time, patients tend to present with symptoms of decreased vision in their 60s and 70s. They often have concurrent cataracts, which may further worsen vision. Cataract surgery in patients with Fuchs’ dystrophy is done a bit differently than in typical patients. (See below for full video) The surgical treatment of Fuchs’ is corneal transplantation, with current techniques of endothelial transplantation being preferred over full-thickness transplantation. These patients may initially do quite well and have improved vision with cataract surgery alone, which is a far simpler surgical procedure. Because Fuchs’ is a progressive disease, endothelial cell function is expected to decline with age. Patients should be informed that cataract surgery may improve or preserve their vision for years, but eventually their corneas may decompensate to the point of requiring future transplantation.