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Unlocking the future of Cannabis sativa through genomics. 🌱 In this episode of Decoding Cannabis, we explore three groundbreaking studies that reshape our understanding of cannabis evolution, diversity, and potential. From the creation of a cannabis pangenome to chromosome-level assemblies and the discovery of rare cannabinoid pathways, this episode covers it all. Topics Covered Lynch et al. (2025) – A 193-genome pangenome reveals surprising diversity in Cannabis sativa, including five population groups, ancient sex chromosome structures, and rare cannabinoid gene pathways shaped by transposable elements. Ryu et al. (2024) – High-quality, chromosome-level genome assembly of the CBD-rich cultivar ‘Pink Pepper’, revealing structural variation hotspots and evolutionary links to Humulus lupulus. Stack et al. (2025) – Seven new phased genomes highlight under-sampled global germplasm, telomere-biased recombination, and improved trait mapping of the EARLY1 flowering locus. References Lynch, R.C. et al. (2025). Domesticated cannabinoid synthases amid a wild mosaic cannabis pangenome. Ryu, B.-R. et al. (2024). Chromosome-level Haploid assembly of Cannabis sativa L. cv. Pink Pepper. Nature Portfolio. Stack, G.M. et al. (2025). Comparison of Recombination Rate, Reference Bias, and Unique Pangenomic Haplotypes in Cannabis sativa Using Seven De Novo Genome Assemblies. Int. J. Mol. Sci., 26(3), 1165. ⚠️ Disclaimer: This podcast was generated with the assistance of AI tools for narration and script preparation. All scientific content has been reviewed and verified by cannabis genomics researchers. The information provided is for educational and informational purposes only and does not constitute medical, legal, or professional advice. Always consult with qualified experts before making decisions related to health, genetics, or regulatory compliance. 🔬 Subscribe to stay informed, curious, and connected to the world of cannabis innovation. #CBDScience #CannabisResearch #CannaInsights #CannabisInnovation #NonTHCTherapeutics #CannabinoidScience #PlantMedicine