Biological Neurotoxins Evaluation in Stem Cell-derived CNS Neurons | Protocol Preview скачать в хорошем качестве

Biological Neurotoxins Evaluation in Stem Cell-derived CNS Neurons | Protocol Preview

Watch the Full Video at https://www.jove.com/v/52361/function.... Functional Evaluation of Biological Neurotoxins in Networked Cultures of Stem Cell-derived Central Nervous System Neurons - a 2 minute Preview of the Experimental Protocol Kyle Hubbard, Phillip Beske, Megan Lyman, Patrick McNutt United States Army Medical Research Institute of Chemical Defense, Research Division, Cellular Molecular Biology Branch; A custom protocol is described to differentiate mouse ES cells into defined populations of highly pure neurons exhibiting functioning synapses and emergent network behavior. Electrophysiological analysis demonstrates the loss of synaptic transmission following exposure to botulinum neurotoxin serotypes /A-/G and tetanus neurotoxin. Visit https://www.jove.com?utm_source=youtu... to explore our entire library of 14,000+ videos of laboratory methods and science concepts. JoVE is the world-leading producer and provider of science videos with the mission to improve scientific research and education. Millions of scientists, educators, and students at 1500+ institutions worldwide, including schools like Harvard, MIT and Stanford benefit from using JoVE's extensive library of 14,000+ videos in their research,education and teaching. Subscribe to our channel:    / jovejournalofvisualizedexperiments