Antifreeze proteins: shaping ice crystal growth скачать в хорошем качестве

Antifreeze proteins: shaping ice crystal growth

Controlling ice crystal growth is a grand scientific challenge with major technological ramifications. We are interested in natural cryo-protective biopolymers, commonly known as antifreeze proteins (AFPs), which halt further growth of nascent ice crystals within a limited subzero temperature range known as the thermal hysteresis gap. This subclass of ice-binding proteins (IBPs) is essential for various species of fish, insects, microorganisms and plants as a coping strategy to live at subzero temperatures. We use state-of-the-art physico-chemical methods to study the various functional roles of IBPs such as freezing point depression, inhibition of ice recrystallization, ice nucleation and ice crystal shaping. We aim to better understand how IBPs function, and exploit these fundamental insights to develop synthetic analogues for application in biomedicine and materials science, focusing in particular on de-icing, anti-icing and cryopreservation. For more information, see: Voets Research Group webpage: http://www.voetslab.nl. Davies, TiBS 2014, 39(11), 548-555 (http://doi.org/10.1016/j.tibs.2014.09.... A.S. Oude Vrielink et al., Biointerphases 2016, 11, 018906 (http://doi.org/10.1116/1.4939462). L.L.C. Olijve et al., PNAS 2016, 113(14), 3740-3745 (http://doi.org/10.1073/pnas.1524109113). L.L.C. Olijve et al., Macromol. Chem. Phys. 2016, 217(8), 951-958 (http://doi.org/10.1002/macp.201500497). Credits: Animation: ICMS Animation Studio Voice-over: Studio Make Music: "Nebulas Night" by Jason Livesay