Giant cell arteritis (Temporal arteritis) Vasculitis Pathology : Usmle Step 1 скачать в хорошем качестве

Giant cell arteritis (Temporal arteritis) Vasculitis Pathology : Usmle Step 1

📌 𝐅𝐨𝐥𝐥𝐨𝐰 𝐨𝐧 𝐈𝐧𝐬𝐭𝐚𝐠𝐫𝐚𝐦:-   / drgbhanuprakash   📌𝗝𝗼𝗶𝗻 𝗢𝘂𝗿 𝗧𝗲𝗹𝗲𝗴𝗿𝗮𝗺 𝗖𝗵𝗮𝗻𝗻𝗲𝗹 𝗛𝗲𝗿𝗲:- https://t.me/bhanuprakashdr 📌𝗦𝘂𝗯𝘀𝗰𝗿𝗶𝗯𝗲 𝗧𝗼 𝗠𝘆 𝗠𝗮𝗶𝗹𝗶𝗻𝗴 𝗟𝗶𝘀𝘁:- https://linktr.ee/DrGBhanuprakash • Giant cell arteritis (temporal arteritis) --------------------------------------------------------------------- • It is the most common form of systemic vasculitis in adults. It is an acute and chronic, often granulomatous inflammation of arteries of large to medium size • the mean age for disease presentation is 76 • Giant cell arteritis affects principally the arteries in the head, especially the temporal arteries which is the extracranial branch of carotid artery • Vertebral and ophthalamic arteries may also be involved. • There is segmental involvement of vessel . Segment of affected artery develops nodular thickening with narrowing of lumen. • There is granulomatous intlammation in the vessel wall with foreign body and Langhans type multinucleated giant cell and fragmentation of internal elastic lamina • Most common symptoms are non-specific constitutional symptoms like fever, fatigue, anorexia and weight loss. • Headache ( temporal ) is the most common vasculitis related symptom. • Jaw daudication is the most specific symptom. Other symptoms are visual symptoms (diplopia, sudden blindness ,arthritis, and polymylagia rheumatic ) • The most serious complication of GCA is blindness, a result of anterior ischemic optic neuropathy caused by ischemia secondary to inflammation of the ophthalmic artery supplying the optic nerve • Blood investigations : Raised ESR and normocytic normochronic anemia • Temporal artery biopsy: this is the gold standard for diagnosis and should be performed when GCA is suspected. • Corticosteroids are the drugs of choice for treatment usmle step 1 pathology dermatology uworld medical school #giantcellarteritis #temporalarteritis #usmle #usmlestep1 #pathology