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Highlights from Oncogene to mark the journal’s 30th anniversary. Visit http://www.nature.com/onc to explore journal content and find more reasons to submit your research. Oncogene aims to make substantial advances in our knowledge of processes that contribute to cancer by publishing outstanding research. The journal propagates work that challenges standard conjecture and builds on previous studies, in particular those that lead to establishing new paradigms in the etio-pathogenesis, diagnosis, treatment, or prevention of cancers, and in processes that drive metastatic spread, and provide important insights into cancer biology beyond what has been revealed thus far. Areas covered by Oncogene include the cellular and molecular biology of cancer including resistance to cancer therapies, and development of better approaches to improving survival. Across cancer biology, the journal has a broad remit encompassing the life sciences and biomedicine, from the most fundamental and theoretical work, through to translational, applied, and clinical research. The journal is proud to celebrate 30 years of publication in 2017, and to extend its tradition of publishing high-impact, widely read research. This video provides a brief impact overview and some highlights to date. Learn more at: http://www.nature.com/onc