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Dr. Iain Campbell, a researcher at the University of Edinburgh, discusses his groundbreaking pilot study on ketogenic therapy for bipolar disorder with Dr. Bret Scher. Having personally experienced the benefits of ketosis for his own bipolar type II depression, Dr. Campbell delves into the link between metabolic health and mental well-being. Dr. Campbell shares how his recent study reveals a correlation between higher ketone levels and improvements in mood, energy, impulsivity, and anxiety in patients with bipolar disorder. He also highlights the intriguing brain imaging results that indicate reductions in brain glutamate, hinting at one of the potential mechanisms behind ketogenic therapy's effectiveness. Key Topics Covered: • The correlation between ketone levels and mood stabilization • Dr. Campbell’s personal journey using ketogenic therapy for bipolar disorder • How ketosis impacts brain glutamate levels • The role of metabolic psychiatry in treating mental illness • The future of metabolic treatments at the newly established UK Metabolic Psychiatry Hub Dr. Campbell's pioneering work at the Metabolic Psychiatry Hub is advancing the field of metabolic psychiatry by integrating research and treatment, demonstrating how ketogenic therapy can be a powerful tool for addressing both metabolic and mental health in the treatment of bipolar disorder. New Study: A Pilot Study of a Ketogenic Diet in Bipolar Disorder: Clinical, Metabolic and Magnetic Resonance Spectroscopy Findings https://doi.org/10.1192/bjo.2024.841 Experts Featured: Dr. Iain Campbell X: @IainCampbellPhD www.metabolicpsychiatryhub.com Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications. Timestamps: 0:00 - Introduction to Dr. Iain Campbell and his groundbreaking study on bipolar disorder and ketogenic therapy 1:57 - Dr. Campbell shares his personal experience with bipolar disorder type 2 and why it was so important for him to do this study on ketogenic interventions for patients with bipolar disorder 5:30 - What does it mean to have bipolar disorder and be euthymic for the inclusion criteria? 6:53 - What did the study reveal about ketones and the improvement of symptoms? Breaking down the key results. 10:25 - Where does Dr. Campbell see this research going next? Future directions and next steps in evaluating ketogenic therapy for mental health. 12:36 - How does the change in glutamate fit into the metabolic overdrive theory? Dr. Campbell explains his research and previous findings. 15:25 - What ketone level should individuals with bipolar disorder aim for? Clinical considerations for those adopting or maintaining a ketogenic diet. 17:28 - How long should someone follow a ketogenic diet for mental health benefits? Insights on treatment duration. 18:21 - What feedback did participants share about their experience? 22:50 - How has the conversation around metabolic health and bipolar disorder evolved at conferences? 24:53 - University of Edinburgh’s metabolic psychiatry hub and its role in advancing research and treatment. 27:23 - Reflections on the study’s impact and what’s next for Dr. Campbell and his team in metabolic psychiatry research. 29:36 - Where to learn more about Dr. Campbell and The Hub for Metabolic Psychiatry #NewTreatmentForBipolar #MetabolicMind #MetabolicNeuroscience #KetogenicMetabolicTherapy #NutritionalKetosis #AlternativeTreatment #PsychiatricMedication #KetogenicTherapy #KetoforBipolar