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The EMJ Podcast | Episode 214 Discover the remarkable progress made in heart failure therapies with Jonathan and Haider Warraich, Director of the Heart Failure Program at VA Boston Healthcare System, Massachusetts, USA. They also discuss the intricacies of heart transplantation and end-of-life care. Speaker bio: Haider Warraich is Associate Director of Heart Failure at VA Boston Healthcare System, Massachusetts, USA, where he leads the Advanced Heart Failure program. He is also Associate Physician at Brigham and Women’s Hospital (BWH), overseeing advanced heart failure and transplantation services while coordinating fellowship programs. Following medical school in Pakistan, Warraich pursued residency at Beth Israel Deaconess Medical Center before advancing to Duke University Medical Center for cardiology training. Returning to Boston in 2019, he assumed leadership roles at the VA and BWH, alongside teaching at Harvard Medical School. Appointed in 2023 as Senior Clinical Advisor for Chronic Disease at the FDA, he influences policy across various domains including drugs, devices, nutrition, tobacco, and AI. Warraich is also a prolific writer, with notable works like ‘Modern Death – How Medicine Changed the End of Life’ (2017), ‘State of the Heart’ (2019), and ‘Song of Our Scars – The Untold Story of Pain’ (2022). 00:00 Introduction 03:28 Warraich’s journey into cardiology 06:15 Recent advances in heart failure therapies 11:15 What is the median survival from diagnosis of heart failure? 14:45 The current state of heart transplantation 20:20 Warraich’s experience in regulatory medicine 24:33 Warraich’s book: ‘Modern Death, How Medicine Changed the End of Life’ 33:45 Warraich’s s book: ‘State of the Heart’ 40:12 Warraich’s most recent book: ‘The Song of Our Scars: The Untold Story of Pain’ 46:13 Warraich’s three wishes for healthcare