Life-Threatening Infections: Early Detection and Treatment of Necrotizing Soft Tissue Infections скачать в хорошем качестве

Life-Threatening Infections: Early Detection and Treatment of Necrotizing Soft Tissue Infections

Welcome to Medical Specialists Associates’ educational series on topics in critical care medicine. I’m Christopher Voss, MD, MS, board-certified in anesthesia, critical care medicine, neurocritical care medicine, and pain medicine. Necrotizing soft tissue infections are severe, life-threatening infections characterized by rapid destruction of the skin, subcutaneous fat, fascia, and muscles. Despite being relatively rare, NSTIs carry high mortality rates, ranging from 10% to 20%, with minimal improvement in outcomes over the past 20 to 30 years. As critical care physicians, understanding the diagnostic challenges, surgical interventions, and antimicrobial management is vital to improving patient outcomes. References: 1. Nawijn F, et al. Time is of the essence when treating necrotizing soft tissue infections: A systematic review and meta-analysis. World J Emerg Surg. 2020;15:4. 2. Hedetoft M, et al. Incidence, comorbidity and mortality in necrotizing soft-tissue infections, 2005-2018: A Danish nationwide register-based cohort study. BMJ Open. 2020;10(10):e041302. 3. May AK, et al. Estimating the impact of necrotizing soft tissue infections in the United States: incidence and re-admissions. Surg Infect (Larchmt). 2021;22(5):509-51