[Webinar] Process development to simplify manufacturing scale up of therapeutic viral vectors скачать в хорошем качестве

[Webinar] Process development to simplify manufacturing scale up of therapeutic viral vectors

0:19 Introduction to the webinar 2:10 Presentation of Polyplus-transfection 2:57 Transfection product lines 3:56 Viral Vectors Manufacturing Roadmap 6:59 Current Upstream Manufacturing Challenges 8:15 Optimized PEI for Viral Vector Production: PEIpro® 12:02 Scaling-up systems: adherent and suspension 14:00 Scalable transient transfection: cell culture medium 18:35 Production scale-up 21:20 PEIpro® product range: from PD with PEIpro® to commercialization with PEIpro®-GMP Q&A Session 24:40 Experiences of viral vector manufacturing and specific pain points in scaling-up 29:45 Adherent VS suspension 36:30 Transfection efficiency factors, which criteria need to be monitored in a dynamic process? 42:50 Importance of supplier relationships as you move to commercial scale? 49:30 Could regulatory agencies ask for a QC on residual presence of PEIpro® within the final product? 50:17 Is Metabolomic used to understand the bioprocess system and how efficient transfection is? 52:55 What further improvements to look for in viral vector manufacturing process? Join this webinar hosted by BioInsight and featured by experts in transfection. Several topics are covered around the optimization of manufacturing scale-up of therapeutic viral vectors to support advanced clinical trials and commercialization.