Mesothelioma vs Pleural Metastasis Radiology - What You Need to Know about Mesothelioma? скачать в хорошем качестве

Mesothelioma vs Pleural Metastasis Radiology - What You Need to Know about Mesothelioma?

Mesothelioma vs Pleural Metastasis Radiology ➡️ http://MesotheliomaUSA.net Fifty-five patients including 29 males and 26 females were evaluated in this study. According to pathology reports, 17 patients (11 males and 6 females) had mesothelioma and 38 patients (18 males and 20 females) were diagnosed with metastatic carcinoma of the pleura (30.9% mesothelioma and 69.1% metastatic carcinoma). On the other hand, according to radiology reports, 22 patients (14 males and 8 females) had mesothelioma and 33 patients (15 males and 18 females) were diagnosed with metastatic carcinoma (40% mesothelioma and 60% metastatic carcinoma). By radiology, 82% of patients with mesothelioma and 79% of patients with metastatic carcinoma of the pleura were diagnosed correctly. Among all 55 cases, the most common finding was pleural thickening (70.9%, n = 39) followed by free pleural effusion (60%) and parenchymal infiltration (56.4%). Based on pathology, we divided our cases into two groups of malignant mesothelioma (17 cases) and metastatic carcinoma (38 cases). Twenty imaging findings were assessed and their frequencies in each group are reported. The most prevalent finding in the mesothelioma group was pleural thickening seen in 88.2% (n = 15) followed by loculated effusion in 58.8%, and thickening of interlobar fissure in 47.1%. The least common finding in the mesothelioma group was hepatic invasion detected in one case. Other findings were observed at least in two cases. Among the metastatic group, the most common finding was free pleural effusion (71.7%, n = 27) and it mostly appeared as massive volumes rather than mild or moderate volumes (55.3% vs. 15.8%). Parenchymal infiltration (65.8%) and pleural thickening (63.2%) were ranked second and third common findings, respectively, with an almost similar prevalence. None of the metastatic cases showed hepatic invasion, but chest wall and intraperitoneal invasion each were seen in one patient. Other findings were detected at least in two patients. 5. Discussion. Malignant pleural mesothelioma is a rare pleural malignancy that is diagnosed by imaging and histology assessment. One of its important differential diagnoses is pleural metastatic carcinoma with several similar imaging findings. In this study, we compared the radiologist and pathologist’s diagnoses on 55 pleural malignancy cases and investigated their CT findings. According to chest CT scans in our study, 14 out of 17 mesothelioma and 30 out of 38 metastatic pleural malignancy cases were diagnosed correctly. It means that 82% of the patients with mesothelioma and 80% of the patients with metastatic carcinoma of the pleura were correctly diagnosed by the radiologist. It shows the high accuracy of CT scan in differentiating these two pleural malignancies. Seely et al. in their study on 92 mesothelioma patients concluded that interobserver agreement (pathology and radiology) was excellent. Moore et al. said that the combination of radiology and acquisition of pathology is essential in the diagnosis of mesothelioma. Senyigit and colleagues mentioned in their study that although CT findings of MPM vary, they may provide a valuable clue to the diagnosis, at least in patients with a history of asbestos exposure. According to our results, the three most common findings of pleural malignancies were pleural thickening, free pleural effusion and parenchymal infiltration. Similarly, in an article by Moore et al., nodular pleural thickening and pleural thickening 1 cm are named as most helpful CT findings suggesting malignant pleural disease. We noticed that tumor invasion to the chest wall, liver and peritoneum are rarely seen among all cases, but they were more common in malignant mesothelioma compared to metastatic carcinoma. In the study performed by Wang et al., it has been mentioned that MPM is locally aggressive with frequent invasion to the chest wall, mediastinum and diaphragm. In our study, among malignant mesothelioma cases, pleural thickening, loculated pleural effusion and thickening of the inter lobar fissure were the most prevalent CT findings and the least common ones were hepatic/chest wall invasion, massive pleural effusion, and pericardial effusion. In metastatic pleural disease cases, free pleural effusion, parenchymal infiltration, and pleural thickening were the most common CT findings and invasion to other organs, pericardial effusion, and thickening had the lowest rate in this disease. Mesothelioma vs Pleural Metastasis Radiology - What You Need to Know about Mesothelioma?    • Mesothelioma vs Pleural Metastasis Radiolo...      / @mesotheliomausa   #chestradiography #pleuraldiseases #malignantmesothelioma #tomography 🔗 https://www.ncbi.nlm.nih.gov/pmc/arti...