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Part 2 of 4 of our series with Roy Maute, CEO and co-founder of Pheast Therapeutics. In this episode of The Biotech Startups Podcast, we follow CEO and co-founder of Pheast Therapeutics, Roy Maute’s graduate school journey in Riccardo Dalla-Favera’s demanding Columbia lab, where he dives into genetic rearrangements in B-cell lymphoma and chooses intensity over comfort to accelerate his growth alongside clinician-scientists. He shares how brutal weekly Friday lab meetings, where imperfect work was publicly dissected, built his resilience and rigor, and what it was like to live through the shift from Sanger to high-throughput sequencing that reshaped cancer research. Roy also reflects on why he never wanted to become a professor and how a mentor’s advice led him to Irving Weissman’s famously hands-off Stanford lab—a stark contrast to his PhD environment, but equally formative for his scientific career. Key topics covered: The Power of Mentorship: Choosing demanding training over comfortable environments for maximum growth Embracing Failure: Weekly presentations of imperfect work building resilience and faster iteration Technological Revolution: Living through the Sanger-to-NGS transition that transformed cancer research Stanford vs. Berkeley Culture: Industry-friendly attitudes and translation focus at Stanford's stem cell institute Early Company Formation: Co-founding Ab Initio Biotherapeutics as a junior postdoc with structural biology collaborators Subscribe to the Podcast: Apple: https://podcasts.apple.com/us/podcast... Spotify: https://open.spotify.com/show/2PSL162... Youtube: / @thebiotechstartupspodcast Website: https://www.thebiotechstartupspodcast... Find our guest, Roy Maute at these links: LinkedIn: / roy-maute-2b31b975 Website: https://www.pheast.com/ Find our host, Jon Chee, at these links: LinkedIn: / jonchee Learn more about Excedr: LinkedIn: / excedr Website: https://www.excedr.com Intro & Outro Songs Created by OkKyojin, Owned by Excedr: Website: https://flow.page/kyojin Resources & Articles: B-cell Lymphoma Genetic Rearrangements: https://www.nature.com/articles/s4140... MicroRNAs in Cancer Biology: https://www.nature.com/articles/s4146... CD47 Macrophage Immunotherapy for Cancer: https://pmc.ncbi.nlm.nih.gov/articles... Cancer Stem Cell Biology and Therapeutic Targeting: https://pmc.ncbi.nlm.nih.gov/articles... High-Throughput DNA Sequencing Technology: https://www.nature.com/articles/s4159... Companies, Universities, & People mentioned: Columbia University: https://www.columbia.edu Stanford University: https://www.stanford.edu University of California, Berkeley: https://berkeley.edu Riccardo Dalla-Favera, MD: https://www.genetics.cuimc.columbia.e... Katia Basso, PhD: https://www.pathology.columbia.edu/pr... Irving Weissman, MD: https://med.stanford.edu/profiles/irv... Timestamps: 00:00 Intro 01:36 Choosing Cancer Research and Academic vs. Industry Paths 06:15 Finding the Right Lab Fit and Demanding Training Environments 07:13 Key Scientific Lessons: Genetics, DNA, and Cancer Biology 12:32 Comfort with Failure and Scientific Training Value 16:56 Storytelling and Communicating Science to Non-Scientists 19:05 Pursuing Postdoc Training and Working with Irv Weissman 25:58 Berkeley vs. Stanford: Academic Culture and Collaboration 28:39 Stanford's Translation-Focused Approach and Industry Engagement 31:39 Co-founding Ab Initio Biotherapeutics During Postdoc 34:09 Outro #BiotechStartups #phdjourney #CancerResearch #ScientificTraining #ImmunotherapyInnovation The Biotech Startups Podcast is powered by Excedr—helping life science startups accelerate R&D and commercialization with founder-friendly equipment leasing.