QA x Immudex - WEBINAR: Evaluation of TCR-pMHC Affinity and its Implications for T Cell Therapies скачать в хорошем качестве

QA x Immudex - WEBINAR: Evaluation of TCR-pMHC Affinity and its Implications for T Cell Therapies

This webinar, in partnership with Immudex, covers: Challenges associated with production of high quality TCR monomers suitable for TCR affinity measurement The importance of TCR affinity measurement in the context of development of T cell therapies Introduction to two techniques used for affinity measurement: Surface Plasmon Resonance and Biolayer Interferometry, and the pros/cons of each technique Results of a case study investigating the interaction between a modified affinity-enhanced TCR targeting the NY-ESO I antigen and its cognate pMHC (HLA-A*0201 / SLLMWITQC) in terms of affinity and kinetics Recommendations on best practices for TCR-pMHC affinity measurement --------- European leader in analytical sciences Quality Assistance S.A. is a leading European Contract Research Organisation providing the pharmaceutical industry with all the analytical services required by EMA and FDA regulations for the development and marketing of innovative human medicinal products. We assist our clients from candidate selection, through non-clinical and clinical studies, to marketing authorisation, using our state-of-the-art, product-dedicated expertise in analytical sciences. For each customer and each project, we design customised solutions, define analytical protocols, develop and validate specific new analytical methods and perform characterisation, stability, pharmacokinetic, biomarker and immunogenicity studies as well as batch release testing, in order to evaluate the Quality, Safety and Efficacy of the given drugs. Technoparc de Thudinie, 2 6536 Donstiennes Belgium www.quality-assistance.com