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Background: Classifying diseases into ICD codes has mainly relied on human reading many written materials, such as discharge diagnoses, chief complaints, medical history, and operation records as the basis for classification. Coding is both laborious and time-consuming because a disease coder with professional abilities takes about 20 minutes per case on average. Therefore, an automatic code classification system can significantly reduce human effort.ICD-10(International Classification of Diseases 10th revision) is a classification of a disease, symptom, procedure, or injury. Diseases are often described inpatients’ medical records with free texts, such as terms, phrases and paraphrases, which differ significantly from those used in ICD-10 classification. Objectives: This paper aims at constructing a machine learning model forICD-10 coding, where the model is to automatically determine the corresponding diagnosis codes solely based on free-text medical notes.Methods: This paper applies Natural Language Processing (NLP) and Recur-rent Neural Network (RNN) architecture with Self-attention mechanism and transformers to classify ICD-10 codes from natural language texts with super-vised learning. Results: Our predicting result can reach F1-score of 0.82 on ICD-10-CM code in the experiments on extensive teleconsultation data. Conclusion: The developed model can significantly reduce human resources in coding time compared with a professional coder. Connect with us: Website: https://databricks.com Facebook: / databricksinc Twitter: / databricks LinkedIn: / databricks Instagram: / databricksinc Databricks is proud to announce that Gartner has named us a Leader in both the 2021 Magic Quadrant for Cloud Database Management Systems and the 2021 Magic Quadrant for Data Science and Machine Learning Platforms. Download the reports here. https://databricks.com/databricks-nam...