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Restless Leg Syndrome

RLS or the Restless Leg Syndrome targets up to 4% of the population with symptoms sufficiently severe to warrant treatment in about 1 in 10 of affected individuals. Manifestations typically occur during the evening hours or while in bed. Inactivity leads to unpleasant sensations in the legs frequently described as burning, aching, tingling, crawling, throbbing or prickling. This uncomfortable feeling present deep in the calf close to the bone leads to the almost uncontrollable urge to move about. Each individual has his or her own method to alleviate the distress. Unfortunately the symptoms of RLS prevent sleep, lead to insomnia and result in excessive daytime sleepiness. Additionally RLS interferes with quiet activities such as reading, driving, watching the television or relaxing after work. The cause of RLS remains a mystery. Low levels of iron within the brain with normal concentration in the blood may be causally associated with RLS. Treatment of RLS remains unsatisfactory with many of the commonly prescribed medicines ultimately worsening RLS after an initial varying period of improvement.