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Your brain is super fragile. So how come it doesn’t get totally wrecked by infections or bacteria? Well, you’ve got this nifty protection called the blood-brain barrier! To help guide us through your brain’s awesome defense, we brought on Catie Profaci, a graduate student at UCSD and a blood-brain barrier expert! Find out more about your brain’s specialized endothelial cells and what happens when the BBB malfunctions. Catie’s writing: https://neuwritesd.org/author/cprofaci/ Catie on Twitter: / cprofaci Pics of Catie in Lab: / badass-hard-at-18833391 In this episode of Neuro Transmissions, Alie and Catie discuss the blood-brain barrier, which is comprised of endothelial cells that protect the brain from potentially dangerous molecules circulating in the blood stream. The video explains the structure of the blood-brain barrier and covers the BBB’s tight junctions. Alie also gets to talk about her favorite brain cell, astrocytes, and how astrocytic end feet also help maintain the blood-brain barrier. Finally, we cover what can happen when the blood-brain barrier breaks down. We hope you enjoy the video and learn a little more about this often-misunderstood part of the brain! Check us out on Patreon - / posts Ryan M. Shaver, Carrie McKenzie, and Raymond Chin are our three Patreon Producers. Thanks you three! You're like the soft glow of a lamp on the pages of an engrossing book. Also, big shoutout to our newest patrons: City Beautiful and KTB! Neuro Transmissions is a channel on a mission to bring neuroscience to everyone. It's not rocket surgery, it's brain science! Learn all sorts of fun and interesting things with Alie Astrocyte and Micah Psych every other Sunday by subscribing to the channel. Have a topic you want covered? Let us know in the comments. Share, like, and subscribe for more videos to come! Over and out. Neuro Transmissions is on the other social medias too: / neurotransmissions / neuroyoutube / neurotransmissions http://www.neurotransmissions.science / neuroyoutube Snapchat - @neuroyoutube **Credits** Footage from The Lord of the Rings: The Two Towers was used for educational purposes and falls under fair use. Vector images from freepik.com “In The Mist” Produced by Trackmanbeatz: www.trackmanbeatz.com The work by Trackmanbeatz is licensed under a Creative Commons Attribution 4.0 International License. https://creativecommons.org/licenses/... All other content is original and/or owned by Neuro Transmissions.