Innate Immunity | Complement System | Immunology | Dr Najeeb скачать в хорошем качестве

Innate Immunity | Complement System | Immunology | Dr Najeeb

#drnajeeb #medicines #pharmacology #innateimmunity #innate #complements Innate Immunity | Complement System | Immunology | Dr Najeeb Like this video? Sign up now on our website at https://www.DrNajeebLectures.com to access 800+ Exclusive videos on Basic Medical Sciences & Clinical Medicine. These are premium videos (NOT FROM YOUTUBE). All these videos come with English subtitles & download options. Sign up now! Get Lifetime Access for a one-time payment of $16 ONLY! Sign up now on our website at https://members.drnajeeblectures.com/ --------------------------------------------------------------------------------------------------------------------------- Why sign up for premium membership? Here's why! Membership Features for premium website members. 1. More than 800+ Medical Lectures. 2. Basic Medical Sciences & Clinical Medicine. 3. Mobile-friendly interface with android and iOS apps. 4. English subtitles and new videos every week. 5. Download option for offline video playback. 6. Fanatic customer support and that's 24/7. 7. Fast video playback option to learn faster. 8. Trusted by over 2M+ students in 190 countries. --------------------------------------------------------------------------------------------------------------------------- ▬▬▬▬▬▬▬▬▬▬ Contents of this video ▬▬▬▬▬▬▬▬▬▬ 0:00 Mechanism of Action 8:10 Antigen X Antibody Reaction 11:30 Complement Protein-C1 Activation 14:50 C1 C4 Helper T cells 18:40 C1 C4B C2B 20:40 C4B C2B C3B Complex 23:10 C3B CONVERTASE 28:10 C6 C7 C8 C9 34:10 GRAM-POSITIVE VS GRAM-NEGATIVE 42:40 MACROPHAGES / NEUTROPHILS Action 46:10 Opsonin's C3B IgG 50:00 Opsonization Process 1:00:40 Endotoxins’ Action On Protein LPS 1:11:00 Alternate Pathway-Mannan 1:14:00 Lectin Pathway 1:22:00 Mast Cell Response 1:28:00 Anaphylatoxin 1:35:00 B Cell Activation 1:37:24 REVIEW --------------------------------------------------------------------------------------------------------------------------- The complement system, also known as complement cascade, is a part of the immune system that enhances (complements) the ability of antibodies and phagocytic cells to clear microbes and damaged cells from an organism, promote inflammation, and attack the pathogen's cell membrane. It is part of the innate immune system, which is not adaptable and does not change during an individual's lifetime. The complement system can, however, be recruited and brought into action by antibodies generated by the adaptive immune system. The complement system consists of a number of small proteins that are synthesized by the liver, and circulate in the blood as inactive precursors. When stimulated by one of several triggers, proteases in the system cleave specific proteins to release cytokines and initiate an amplifying cascade of further cleavages. The end result of this complement activation or complement fixation cascade is stimulation of phagocytes to clear foreign and damaged material, inflammation to attract additional phagocytes, and activation of the cell-killing membrane attack complex. Over 30 proteins and protein fragments make up the complement system, including serum proteins, and cell membrane receptors. They account for about 10% of the globulin fraction of blood serum. The innate immune system is one of the two main immunity strategies found in vertebrates (the other being the adaptive immune system). The innate immune system is an older evolutionary defense strategy, relatively speaking, and is the dominant immune system response found in plants, fungi, insects, and primitive multicellular organisms. --------------------------------------------------------------------------------------------------------------------------- Join this channel to get access to perks: Sign up now on our website at https://members.drnajeeblectures.com/...    / @doctornajeeb   Follow us on Facebook :-   / drnajeeb   Follow us on Instagram :-   / drnajeeblectures