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Pericardial mesothelioma is an extremely rare form of cancer that affects the pericardium, the lining around the heart. Here are some key points about it: Causes The primary cause of pericardial mesothelioma is believed to be asbestos exposure. However, only a small percentage of cases have been directly linked to asbestos2. Other potential risk factors include exposure to erionite, radiation, thorotrast (a historical contrast agent), and certain infections. Symptoms Symptoms of pericardial mesothelioma can be nonspecific and may include: Chest pain Shortness of breath Heart palpitations Fatigue Pericardial effusion (fluid buildup around the heart) Diagnosis Diagnosing pericardial mesothelioma can be challenging due to its rarity and nonspecific symptoms. Imaging tests such as X-rays, CT scans, and echocardiograms are often used to detect tumors in the pericardium1. Treatment Treatment options for pericardial mesothelioma are limited and may include: Surgery to remove the tumor Chemotherapy to target cancer cells Radiation therapy in some cases, although it carries higher risks near the heart Prognosis The prognosis for pericardial mesothelioma is generally poor, with a median survival time of about 2 to 6 months after diagnosis. However, some patients may live longer with aggressive treatment. #Mesothelioma