Viral Vectors скачать в хорошем качестве

Viral Vectors

Viral vectors have become increasingly powerful tools for gene transfer in a variety of applications. In experimental systems, they efficiently deliver nucleic acids to many cell types, both in tissue culture and animal models. In recent years, they have also been placed at the forefront of modern medicine; viral vectors have found encouraging new roles in vaccines and in gene therapy for the treatment of several cancers and diseases. While different viral vectors, including adenoviruses, retroviruses, and adeno-associated viruses, should share several key properties allowing for transgene expression, they must be tailored to their specific purpose. In this edition of the Technical Seminar Series, Ariana Arduini, a MSc student in the Liang Lab, discussed the general characteristics and uses of available viral vectors in laboratory and clinical settings, and how to appropriately select a vector based on your experimental goals. This seminar also described a protocol to safely assemble viral vectors for downstream genetic modification experiments.