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An organized structure that supports immune responses. (Types) • primary lymphoid tissues (central lymphoid organs): The sites of the formation and development of lymphocytes. I.e. bone marrow, thymus. • secondary lymphoid tissue (peripheral lymphoid organs): Maintain mature naïve lymphocytes and initiate adaptive immune responses. E.g. lymph nodes, spleen, tonsils, Peyer's patches, appendix, mucosa-associated lymphoid tissue, nasal-associated lymphoid tissue. (Examples of group of lymphoid tissue) • Mucosa-associated lymphoid tissue (MALT): A network of lymphoid cell aggregates and tissue that is distributed in submucosal layers of the gastrointestinal, genital, respiratory, and urinary tracts, as well as in the eyes, skin, thyroid, breasts, tonsils, and salivary glands. • Nasal-associated lymphoid tissue (NALT): An organized lymphoid tissue in the nasal mucosa with aggregates of lymphocyte like follicles and infiltration of the overlying epithelium of all the different parts of the nasal cavity. • Gut-associated lymphoid tissues (GALT): The tonsils, adenoids, appendix, and Peyer's patches. • Bronchial-associated lymphoid tissue (BALT): The respiratory epithelium.