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In this episode of Curing with Sound, Lynn Dengel, MD, a surgical oncologist at UVA Health, discusses her groundbreaking clinical trial combining focused ultrasound with immunotherapy to treat patients with advanced melanoma. She shares insights into how this Foundation-funded trial – which is still enrolling patients – could help those who don't benefit from standard immunotherapy alone. Key points from the conversation: • Melanoma is the most invasive type of skin cancer and accounts for the majority of skin cancer deaths. More than 100,000 Americans are diagnosed with melanoma each year. • The study will enroll approximately 11 participants with advanced melanoma who are receiving a cancer immunotherapy drug (PD-1 antibody blockade) as part of their regular care and having the melanoma surgically removed. • Dr. Dengel explains how focused ultrasound not only targets tumor tissue but may also create an enhanced environment for immunotherapy to work more effectively. • As a senior advisor to the Foundation's immunotherapy program, Dr. Dengel highlights the value of cross-institutional collaboration in advancing focused ultrasound research and improving patient outcomes. UVA Health Study: Seeking Adult Patients with Advanced Melanoma Who are Receiving Immune Therapy and Who are Planning to Receive Surgery - MORE INFO (https://uvahealth.com/clinicaltrials/...) EPISODE TRANSCRIPT (https://turboscribe.ai/transcript/sha...) ---------------------------- QUESTIONS? Email [email protected] (mailto:[email protected]) if you have a question or comment about the show, or if you would you like to connect about future guest appearances. Email [email protected] (mailto:[email protected]) if you have questions about focused ultrasound or the Foundation. FUSF SOCIAL MEDIA • LinkedIn ( / fusfoundation ) • X ( / fusfoundation ) • Facebook ( / focusedultrasound ) • Instagram ( / fusfoundation ) • TikTok ( / fusfoundation ) • YouTube ( / @fusfoundation ) FUSF WEBSITE https://www.fusfoundation.org (https://www.fusfoundation.org/) SIGN UP FOR OUR FREE NEWSLETTER https://www.fusfoundation.org/newslet... READ THE LATEST NEWSLETTER https://www.fusfoundation.org/the-fou... DOWNLOAD "THE TUMOR" BY JOHN GRISHAM (FREE E-BOOK) https://www.fusfoundation.org/read-th...