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Presented by: Katherine Fuller, PGY3, Marina Atalla, PGY3, Sarah Ge, PGY3 Supervisor: Dr. Siraj Mithoowani Objectives: Review and understand the systemic manifestations and diagnostic features of HLH Describe the common causes and triggers for HLH Review treatment options for HLH ---- McMaster University’s, Department of Medicine Grand Rounds (MGR), combined with Hamilton Health Sciences and St. Joseph’s Healthcare Hamilton, is held on rotation every Thursday via ‘Teams’ and uploaded to our channel weekly. For more information on the Department of Medicine, Faculty of Health Sciences, at McMaster University: https://healthsci.mcmaster.ca/medicine Follow us on Twitter @MacDeptMed For more information on Hamilton Health Sciences (HHS): https://www.hamiltonhealthsciences.ca/ Follow HHS on Twitter: @HamHealthSci For more information on St. Joseph’s Healthcare Hamilton (SJHH): https://www.stjoes.ca/ Follow us SJHH Twitter: @STJOESHAMILTON ----- We acknowledge with gratitude and respect that McMaster University, Hamilton Health Sciences, and St. Joseph’s Healthcare Hamilton, stand on the traditional territory shared between the Haudenosaunee confederacy and the Anishinabe nations, recognized in the Dish with One Spoon Wampum belt treaty.