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detailed look at both the clinical assessment process and the management of major musculoskeletal system disorders. One document focuses on the pathology, systemic effects, and pharmacological treatment of various conditions, specifically addressing Autoimmune Diseases like Rheumatoid Arthritis and chronic disorders such as Gout and Osteoporosis. This source provides extensive details on specific drug prototypes, including their mechanisms of action, adverse effects, and necessary nursing implications for safe administration, such as monitoring for potential infection or Hepatotoxicity. The second source provides a systematic, step-by-step guide for performing a physical Musculoskeletal System Assessment, instructing clinicians on proper inspection, palpation, and testing of major joints. This assessment protocol includes evaluating Range of Motion, grading Muscle Strength on a 0–5 scale, and performing crucial Neurovascular Checks (CMS) if an injury is suspected.