Breakthroughs in Proteomics & Single Molecule Protein Sequencing скачать в хорошем качестве

Breakthroughs in Proteomics & Single Molecule Protein Sequencing

Modern DNA-sequencing methods can interrogate single molecules in extremely high throughput, but protein sequencing typically uses ensemble techniques and requires larger amounts of relatively pure material. Reed et al. generated a set of labeled proteins that recognize the first few amino acids at the N terminus of a peptide immobilized on an optical chip. Transient binding yields spectral signals and association and dissociation rates that can be used to identify the terminal amino acid. Multiple amino acids on a single molecule can then be read by adding a protease that gradually reveals the next amino acid at the terminus. #biotechnology #science #vc #startup #startups #startupideas #biology #biotech #chemistry #business #speech #speeches #investing #investment #lifescience #casestudy #scientist #scientists #inventors #inventor #inventions #invention #research #innovation #siliconvalley #entrepreneur #entrepreneurship #entrepreneurs #healthcare #genomics #genetics #history #biologia #technology #tech #founderstories #founder #founders #founderstory #scienceandtechnology #sciencestory #stories #bioengineering #engineering #engineer #biochemistry #discovery #discover #technical #health #education #educational #learning #learn #podcast #podcasts #podcasting #podcaster #technews Axial Newsletter: https://axial.substack.com/ Build with Axial: https://build.axialvc.com/ https://linktr.ee/axialxyz