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In this video, I explain and compare the microscopic features of Epidermoid, Dermoid, and Trichilemmal cysts, focusing on how to differentiate them under the microscope. These are common cystic lesions of skin and scalp, yet they often cause confusion in exams and slide discussions. Here, I describe each lesion clearly with labeled microscopy images and point-wise comparison. You’ll learn about: 🔹 Epidermoid cyst – cyst lined by stratified squamous epithelium with granular layer and lamellated keratin inside 🔹 Dermoid cyst – similar epithelial lining with skin adnexal structures (hair follicles, sebaceous glands) in the cyst wall 🔹 Trichilemmal (pilar) cyst – lined by abrupt keratinization without granular layer, filled with dense eosinophilic keratin, commonly seen on scalp I also summarize the key differentiating points, common sites, and diagnostic clues useful for viva and practical exams. Chapters: 0:00 – Introduction 0:25 – Epidermoid cyst microscopy 2:23 – Dermoid cyst microscopy 3:43 – Trichilemmal (pilar) cyst microscopy 4:46 – Comparative summary table #Pathology #SkinPathology #EpidermoidCyst #DermoidCyst #TrichilemmalCyst #PilarCyst #Histopathology #MicroscopySlides #GrossAndMicroscopy #PathologyEducation #DrAshmita #MedicalLearning