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Use of the ICU Liberation Bundle (A-F) has been shown to decrease delirium, coma, restraint use, transfer to skilled nursing facilities, readmissions, ICU and hospital lengths of stay, and mortality and significantly reduce healthcare costs. Use of the bundle has decreased dramatically during the COVID-19 pandemic. This session at SCCM’s 2023 Critical Care Congress aimed to help ICU teams improve bundle compliance and performance during and after the pandemic. Resuscitating the Letter A: Assess, Prevent, and Treat Pain Michele C. Balas, CCRN-K, PhD, RN, University of Nebraska Medical Center College of Nursing Resuscitating the Letter B: Both Spontaneous Awakening and Breathing Trials Niall Prendergast, UPMC Presbyterian Resuscitating the Letter C: Choice of Analgesia and Sedation Joanna Stollings, PharmD, FCCM, Vanderbilt University Medical Center Resuscitating the Letter D: Assess, Prevent, and Treat Delirium Juliana Barr, MD, FCCM, VA Palo Alto Resuscitating the Letter E: Early Mobility and Exercise Christiane S. Perme, PT CCS, FCCM, Houston Methodist Hospital Resuscitating the Letter F: Family Engagement and Involvement Jaspal Singh, MD, MS, FCCM, Carolinas Medical Center