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There’s a silent gap in Medical Communications—and it’s not about effort, it’s about alignment. In this episode of Transforming Medical Communications, host Wesley Portegies is joined by Simon Priou, an experienced global content leader, to unpack the persistent challenges between Global, Regional, and Local teams. This conversation goes beyond content production—it reveals the human dynamics and workflow challenges that often prevent globally developed materials from being adapted, adopted, or impactful at the local level. Whether you’re building affiliate toolkits or bridging silos, this episode offers a strategic lens on what actually enables trust, usability, and relevance across regions. In this episode, you’ll learn how to: Move from ‘content push’ to ‘collaborative pull’ by engaging regions and countries early Localize with precision without compromising science or timelines Identify the trust blockers that quietly erode alignment Close the loop with feedback that drives measurable improvement Before you hit play, ask yourself: Are you creating content that travels—or content that lands? 👉Simon Priou on LinkedIn: / simon-priou 👉Wesley Portegies on LinkedIn: / wesleyportegies 👉MedComms Experts Website: https://www.medcomms-experts.com/ Disclaimer: The opinions and views expressed by the guest are their own and do not represent any past or current employers. Chapters [00:00] Intro [02:20] Why Great Content Fails (And How to Fix It) [05:30] Internal Communication as a Strategic Channel [08:10] Why One-Size-Fits-All Is Over (For Good) [10:50] Internal Omnichannel Strategy [14:40] Closing the Feedback Loop with Affiliates [18:00] Managing Conflicting Inputs Across Regions [22:20] From Content Distribution to Internal Enablement [26:00] Final Thoughts