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Unveiling the Enigma: Exploring Microcystic Lymphatic Malformations Embark on a scientific journey with our latest video as we delve into the fascinating world of microcystic lymphatic malformations! Join us as we break down complex research using mouse models to understand the genetic intricacies behind these rare anomalies. Discover the role of the PIK3CA gene and how its mutations set the stage for the development of microcystic lymphatic malformations. Ever wondered about the different forms these malformations take? From large fluid-filled cysts in the head and neck region to small infiltrating channels deep within tissues, we've got the details covered. Uncover the mystery of a unique population of cells marked by the high expression of PTX3. Learn how these cells trigger hyperproliferation and migration, setting off an immune response that contributes to the sustained growth of these malformations. Excitingly, our video explores potential therapeutic interventions, from inhibiting paracrine signaling to limiting the expansion of these anomalies. Get insights into the latest research beyond embryonic models, as we explore microcystic lymphatic malformations in internal organs. Science meets discovery in this illuminating video that promises to unravel the mysteries of microcystic lymphatic malformations. Hit play and join us on a quest for knowledge and potential breakthroughs!