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We’ve examined the complexities of type 2 diabetes many times on The Proof, learning from experts from across the world. Today, I sit down with a scientist who has fundamentally changed our understanding of this disease: Professor Roy Taylor. As one of the most esteemed scientists researching nutrition and metabolic health, Professor Taylor offers an absolute masterclass in what causes type 2 diabetes and the path towards remission for those managing it. 👇 Visit The Proof website for the full show notes. 👇 https://theproof.com/podcast/ Professor Roy Taylor brings to the table not just his role as Professor of Medicine and Metabolism at Newcastle University but a track record of innovative research that has reshaped diabetes management. His pivotal 2011 discovery that type 2 diabetes could be reversed through the reduction of excess fat in the liver and pancreas sparked a transformation in treatment approaches, culminating in the implementation of the NHS Type 2 Diabetes Path to Remission programme. Beyond his clinical breakthroughs, Professor Taylor's contribution to the prevention of diabetes-related blindness in the UK and his authoritative publications have made him an influential voice in the conversation around diabetes and metabolic health. We discuss: 00:00 - Introduction to the Twin Cycle Hypothesis & Onset of Diabetes 02:25 - Delving into the Twin Cycle Hypothesis: Diabetes Aetiology Explained 14:08 - Risks Associated with High Blood Glucose Levels 20:53 - Key Factors Causing Insulin Resistance in Muscles 26:14 - Understanding the Personal Fat Threshold in Diabetes Onset 35:07 - Assessing the Risk Factors for Developing Type 2 Diabetes 41:12 - Preventative Measures Against Type 2 Diabetes 46:54 - Are Continuous Glucose Monitors Beneficial for Non-Diabetics? 50:15 - Investigating the Determinants of Body Fat Distribution 56:09 - Summary of the DiRECT Trial: Examining the Twin Cycle Hypothesis with Roy Taylor 1:15:48 - Effective Strategies for Type 2 Diabetes Remission 1:29:29 - The Role of Diet Quality in Insulin Sensitivity Improvement 1:36:52 - Examining the Link Between Protein Consumption and Type 2 Diabetes 1:39:34 - Incorporating Exercise into Type 2 Diabetes Remission Plans 1:49:38 - The Possibility of Eradicating Type 2 Diabetes Societally 1:53:24 - Understanding the Reversal of Type 2 Diabetes: Current Insights 1:56:37 - Final Thoughts: The Prospects for Diabetes Management It was an absolute honour to have Professor Taylor on the show for this conversation. As a pioneer and highly respected figure in nutrition and diabetes research, his insight offers unparalleled clarity into both the simplicity and nuance of this prolific disease. If you found this episode valuable, please make sure to pass it on to someone who may benefit from it. Connect with Professor Roy Taylor: Learn more about his work: https://go.ncl.ac.uk/diabetes-reversal Life Without Diabetes book: http://amazon.com.au/Life-Without-Dia... Your Simple Guide to Reversing Diabetes book: http://amazon.com.au/Your-Simple-Guid... If you have any additional questions you would like answered in the future, let me know in the comments. Optimise your health with InsideTracker’s biomarker analysis. Get exclusive access to InsideTracker’s new ApoB test and a 20% discount on your first order at insidetracker.com/simon The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends Enjoy, friends. Simon Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit https://theproof.com/friends/. • The Proof with Simon Hill - https://theproof.com/podcast/ • Book: The Proof is in the Plants - https://theproof.com/book/ • Apple Podcast - https://podcasts.apple.com/gb/podcast... • Spotify - https://open.spotify.com/show/7bAIJCV... • Instagram - / theproof • Twitter - / theproof • Facebook - / theproofwithsimonhill • Plant-Based Ferments Guide - https://theproof.com/ferments/ • Two-week meal plan - https://theproof.com/mealplan/ • Plant Performance - https://theproof.com/plant-performance/ • Use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends.