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A 42-year-old woman with morbid obesity (BMI 42 kg/m²), prediabetes, and hypertension underwent a comprehensive weight-management program combining Roux-en-Y gastric bypass, structured lifestyle modification, and metabolic monitoring. Before surgery, she faced severe fatigue, breathlessness, and limited mobility. After surgery and guided follow-up, she achieved a 28 kg weight loss, normalized blood pressure, and HbA1c reduction from 6.1% to 5.5%. Post-operative care included nutritional supplementation, gradual exercise, and behavioral counseling for dietary adherence. Multidisciplinary support—surgeon, endocrinologist, dietitian, and psychologist—was key to sustaining progress. Beyond weight loss, the patient experienced enhanced energy, reduced joint pain, and improved quality of life. This case illustrates how combining surgery with lifestyle and metabolic care ensures durable outcomes, prevents micronutrient deficiencies, and minimizes relapse risk. Long-term success in obesity management depends on continuous monitoring, patient motivation, and structured rehabilitation—transforming surgery from a single intervention into a holistic, life-changing therapy. A 42-year-old woman achieved lasting weight loss and metabolic recovery after Roux-en-Y gastric bypass, guided by multidisciplinary care and lifestyle optimization. to learn more - https://hidocdr.com/articles/3c66dd74... #BariatricSurgery #ObesityManagement #MetabolicHealth #WeightLoss #LifestyleMedicine #Endocrinology #GastricBypass #Nutrition #BehavioralTherapy #DiabetesPrevention #CardiometabolicCare #MedicalCase