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Here is an illustrated review of steps in percutaneous transluminal coronary angioplasty (PTCA) of left anterior descending (LAD) coronary artery. Description at: https://johnsonfrancis.org/profession... Guidewire is cautiously passed across the total occlusion taking care that it does not produce a false lumen. If the wire is able to pass back and forth easily into multiple side branches, we can be sure that the wire is in the true lumen. There should not any contrast staining or extravasation with check shots of angio. Balloon is passed over the guidewire and inflated and deflated with the indeflator. Patient status and ST segment on the ECG monitor are watched during inflation, though no change is likely while inflating a total occlusion. If it was a near total occlusion or tight stenosis, there is a high chance of angina, ST shift and even hypotension or arrhythmia during balloon inflation, especially if it is prolonged. The deflated balloon is then removed from the coronary artery and the catheter slowly, under negative pressure, taking care not to displace the guidewire.