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Classical variants of Meningioma Tumor

🧠 Classical Variants of Meningioma Tumors Meningiomas are the most common primary intracranial tumors, typically arising from the arachnoid cap cells of the meninges. The World Health Organization (WHO) classifies meningiomas into several histological subtypes, with three classical variants accounting for approximately 80% of all cases. 🧬 Three Classical (Typical) Variants Variant Description Imaging Features Meningothelial Meningioma Most common subtype; composed of polygonal cells with indistinct borders forming whorls Homogeneous, well-circumscribed mass; often hyperintense on T2-weighted MRI Fibrous (Fibroblastic) Meningioma Composed of spindle-shaped cells and abundant collagen Isointense or hypointense on T2; may show calcifications Transitional (Mixed) Meningioma Features of both meningothelial and fibrous types; whorls and fascicles intermixed Variable imaging; may mimic either of the above depending on dominant component These variants are typically WHO Grade I, meaning they are benign and slow-growing, with a favorable prognosis after surgical resection. 🧪 Histological Diversity Beyond the Classical Types The WHO classification includes 15 histological subtypes, some of which are less common and may be associated with atypical or malignant behavior (Grade II or III). These include: Psammomatous Angiomatous Microcystic Clear cell Chordoid Papillary Rhabdoid Each has distinct histopathological and imaging features that can influence treatment and prognosis2. #Meningioma