CN 1: Olfactory Nerve (Scheme, Pathway, Clinical Relevance) | Neuroanatomy скачать в хорошем качестве

CN 1: Olfactory Nerve (Scheme, Pathway, Clinical Relevance) | Neuroanatomy

Content: 0:00 Introduction 00:49 Olfactory Nerve Scheme 02:43 Olfactory Nerve and Epithelium 04:11 How Do We Detect Smells? 06:14 Mechanism of Odorant Signal Transduction 07:20 Olfactory Nerve 08:00 Olfactory Bulb 09:27 Olfactory Pathway 10:12 Lateral Olfactory Stria 14:13 Medial Olfactory Stria 14:40 Intermediate Olfactory Stria 15:15 Anosmia and Dysosmia 18:29 Recap ------------------------------- 🫀 Join:    / @taimtalksmed   📷 Follow my IG:   / taimtalksmed   💝 Donation link: https://www.buymeacoffee.com/taimtalk... ------------------------------- Olfactory Scheme / Overview: Smell - Olfactory Nerves - Olfactory Bulb - Olfactory Tract - Olfactory Trigone - Lateral Stria, Medial Stria and Intermediate stria Olfactory Epithelium: Pseudostratified Columnar epithelium (supporting cells) Consists of: Basal Cells, Sustentacular Cells, Olfactory gland cells (Bowmans glands), Olfactory receptor neurons Olfactory neurons are bipolar neurons How we detect smell: Odorants enters nasal cavity through either nasal opening or nasopharynx. Olfactory Neuron: Dendrites detect smell through a g-protein couples membrane receptor. Signals pass through the cell body and axon Axons form nerve bundles (fila olfactoria) Olfactory Bulb (bulbus olfactorius): Mitral Cells Olfactory Glomerulus (glomeruli) Tufted Cells Amacrine Granular Cells Periglomerular Cells Olfactory Pathway: Olfactory Bulb to the Olfactory Tract When the tract gets closer to the olfactory tract, it widens as the Olfactory Trigone (trigonum olfactorium) and divides into Lateral olfactory stria, Medial olfactory stria and intermediate olfactory stria. Lateral Olfactory Stria (stria olfactoria lateralis) Towards Primary Olfactory Cortex, which sends information to secondary olfactory cortex Medial Olfactory Stria (stria olfactoria medialis): Go towards the subcallosal gyrus (part of limbic system) Intermediate Olfactory Stria (stria olfactoria intemedialis): Goes towards the olfactory Tubercle (part of the limbic system and the rewards system) Clinical Relevance: Anosmia: Temporary or permanent loss of the sense of smell Dysosmia: Distortion of the perception of smell Parosmia: Normal smell smell and taste unpleasant/disgusting Phantosmia: Detect smells that aren't really there in your envirnoment Sources: Singh, I. (2017). Human neuroanatomy (10th ed.). Olfaction: The Sense of Smell (biology-pages.info) Physiology, Olfactory - StatPearls - NCBI Bookshelf (nih.gov) Olfactory Nerve | Radiology Key Frontiers | Effects of odor on emotion, with implications (frontiersin.org) Other sources used; Helwany M, Bordoni B. Neuroanatomy, Cranial Nerve 1 (Olfactory) [Updated 2023 Aug 14]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NB... Kozlowski, T. (2017). Memorix Anatomy: The Complete Study Guide. 2nd ed. Thieme Medical Publishers.