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Diabetes and obesity are two highly prevalent chronic illnesses within today’s society, projected to cause millions of fatalities annually. This video will take you through an overview of these conditions, including a discussion of the pathology and symptoms, with a major focus on brown fat and its potential as a treatment option in the foreseeable future. This video was made by McMaster students Aniqa Chaudhry, Mohammad Farzbod, and Danial Aminaei in collaboration with the McMaster Demystifying Medicine Program. Subscribe to the McMaster Demystifying Medicine YouTube channel: / demystifyingmedicine This video is provided for general and educational information only. Please consult your health care provider for Information about your health. Copyright McMaster University 2020 References Al-Goblan, A. S., Al-Alfi, M. A., & Khan, M. Z. (2014). Mechanism linking diabetes mellitus and obesity. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, 7, 587–591. https://doi.org/10.2147/DMSO.S67400 Diabetes. (n.d.). Retrieved October 30, 2020, from https://www.who.int/news-room/fact-sh... Hildebrand, S., Stümer, J., & Pfeifer, A. (2018). PVAT and its relation to brown, beige, and white adipose tissue in development and function. In Frontiers in Physiology. https://doi.org/10.3389/fphys.2018.00070 Kumar Khemka, V., & Banerjee, A. (2017). Metabolic risk factors in obesity and diabetes mellitus: Implications in the pathogenesis and therapy. Integrative Obesity and Diabetes, 3(3). https://doi.org/10.15761/IOD.1000179 Ramachandran, A. (2014). Know the signs and symptoms of diabetes. The Indian Journal of Medical Research, 140(5), 579–581. Sacks, H., & Symonds, M. E. (2013). Anatomical Locations of Human Brown Adipose Tissue. Diabetes, 62(6), 1783–1790. https://doi.org/10.2337/db12-1430 Wang, C. H., Lundh, M., Fu, A., Kriszt, R., Huang, T. L., Lynes, M. D., Leiria, L. O., Shamsi, F., Darcy, J., Greenwood, B. P., Narain, N. R., Tolstikov, V., Smith, K. L., Emanuelli, B., Chang, Y. T., Hagen, S., Danial, N. N., Kiebish, M. A., & Tseng, Y. H. (2020). CRISPR-engineered human brown-like adipocytes prevent diet-induced obesity and ameliorate metabolic syndrome in mice. Science Translational Medicine. https://doi.org/10.1126/scitranslmed....