10. Vasodilators: Introduction: Anti- Hypertensive Drugs: CVS Pharmacology USMLE Step 1 скачать в хорошем качестве

10. Vasodilators: Introduction: Anti- Hypertensive Drugs: CVS Pharmacology USMLE Step 1

📌𝗝𝗼𝗶𝗻 𝗢𝘂𝗿 𝗧𝗲𝗹𝗲𝗴𝗿𝗮𝗺 𝗖𝗵𝗮𝗻𝗻𝗲𝗹 𝗛𝗲𝗿𝗲:- https://t.me/bhanuprakashdr 📌 𝐅𝐨𝐥𝐥𝐨𝐰 𝐨𝐧 𝐈𝐧𝐬𝐭𝐚𝐠𝐫𝐚𝐦:-   / drgbhanuprakash   📌𝗦𝘂𝗯𝘀𝗰𝗿𝗶𝗯𝗲 𝗧𝗼 𝗠𝘆 𝗠𝗮𝗶𝗹𝗶𝗻𝗴 𝗟𝗶𝘀𝘁:- https://linktr.ee/DrGBhanuprakash 10. Vasodilators: Introduction: Anti- Hypertensive Drugs: CVS Pharmacology -------------------------------------------------------------------------------------------------------------------------- Vasodilators: Introduction – Anti-Hypertensive Drugs – CVS Pharmacology Overview - Vasodilators are a class of antihypertensive drugs that work by relaxing blood vessels (vasodilation 🏞️), leading to reduced vascular resistance 🩸, lower blood pressure 🩺, and improved blood flow 💓. These drugs play a crucial role in the management of hypertension (HTN) 🚦, heart failure 💔, and angina 💢 by reducing the workload on the heart and improving oxygen delivery to tissues. 🔹 Mechanism of Action 🧬- Vasodilators directly act on vascular smooth muscle by increasing nitric oxide (NO) 🧪, blocking calcium entry 🚫, or opening potassium channels ⚡, leading to smooth muscle relaxation and lowered blood pressure. 🔹 Types of Vasodilators & Key Drugs 💊- 1️⃣ Direct Arterial Vasodilators – Act on arteries to lower afterload 🏋️. Hydralazine – Used in severe hypertension 🚨, hypertensive emergencies, and heart failure 💓 (especially in combination with nitrates). Minoxidil – A powerful arterial vasodilator, used in refractory hypertension, but also promotes hair growth (Rogaine) 🦱. 2️⃣ Nitrates (Venous & Arterial Dilators) 🏞️ – Reduce preload & myocardial oxygen demand, used for angina & heart failure. Nitroglycerin – Rapidly relieves angina 💢 and reduces cardiac workload ❤️. Isosorbide Dinitrate – Used in chronic heart failure & ischemic heart disease 🏥. 3️⃣ Calcium Channel Blockers (CCBs) 🚫🧪 – Inhibit calcium entry, reducing vascular tone & contractility. Amlodipine, Nifedipine – Used in hypertension and coronary artery disease. Diltiazem, Verapamil – Have additional effects on heart rate & conduction ⚡, making them useful for arrhythmias. 4️⃣ Potassium Channel Openers ⚡ – Cause hyperpolarization, leading to vasodilation. Diazoxide & Minoxidil – Used in hypertensive crises & severe HTN 🚨. 🔹 Clinical Uses 🏥- Hypertension (HTN) 🚦 – First-line or adjunct therapy for BP control. Heart Failure (CHF) 💓 – Reduce cardiac workload & improve perfusion. Angina 💢 – Improve myocardial oxygenation. Hypertensive Crisis 🚨 – Rapid BP reduction in emergencies. 🔹 Side Effects ⚠️ - Reflex tachycardia 💓, fluid retention 💦, headache 🤕, flushing, and hypotension 🚨. Some drugs (hydralazine) can cause drug-induced lupus-like syndrome 🦋. Vasodilators remain a key class of antihypertensive drugs, providing effective BP control & cardiovascular protection when used properly 🌿✨. #Vasodilators 💊 #AntiHypertensives 🚦 #CVSPharmacology 🩺 #BloodPressureControl 🩸 #HeartFailureDrugs 💓 #NitricOxideEffect 🧪 #CalciumChannelBlockers 🚫🧬 #Nitrates 🏞️ #MedicalEducation 📚 #MBBSNotes #StudySmart 🧠 #SafeCardiacTherapy ❤️ #HypertensionManagement 🚨 #VascularHealth 🏥#medicalanimations #fmge #fmgevideos #rapidrevisionfmge #fmge2024 #mbbslectures #nationalexitexam #nationalexittest #neetpg #usmlepreparation #usmlestep1 #fmge #usmle #drgbhanuprakash #medicalstudents #medicalstudent #medicalcollege #neetpg2025 #usmleprep #usmlevideos #usmlestep1videos #medicalstudents #neetpgvideos #usmlestep2videos