Pediatric Cholestatic Diseases & PFIC – What Every Hepatologist Should Know скачать в хорошем качестве

Pediatric Cholestatic Diseases & PFIC – What Every Hepatologist Should Know

Join Dr. Carina Kugelmas, pediatric nutrition specialist at Denver Health, and Dr. Rima Fawaz, pediatric hepatologist and Medical Director of Pediatric Liver Transplantation at Yale, as they explore the often-overlooked causes of cholestatic liver disease in children. This in-depth conversation takes a closer look at progressive familial intrahepatic cholestasis (PFIC) and other pediatric cholestatic disorders, covering key diagnostic strategies including bilirubin fractionation, bile acid profiling, genetic testing, and GGT levels. The discussion also highlights supportive care, fat-soluble vitamin supplementation, nutritional management, and the latest advancements in treatment—such as IBAT inhibitors (odevixibat, maralixibat)—that have transformed the landscape of pediatric liver care and reduced the need for transplant due to severe pruritus. Learn how early diagnosis, genetic insights, and targeted therapies are improving outcomes, quality of life, and growth in children affected by these rare but serious conditions. Ideal for pediatricians, gastroenterologists, hepatologists, and nutrition experts looking to stay up to date on cutting-edge care in pediatric liver disease. #PediatricLiverDisease #CholestaticLiverDisease #PFIC #PediatricHepatology #BileAcidDisorders #GeneticTesting #BilirubinFractionation #GGTLevels #IBATInhibitors #Odevixibat #Maralixibat #FatSolubleVitamins #PediatricNutrition #LiverTransplantation #RareLiverDiseases #PediatricGI #PruritusRelief #EarlyDiagnosis #LiverHealth #PediatricCare