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In episode 315 of the Stem Cell Podcast, we chat with Drs. Shuibing Chen and Hans Clevers, members of the Steering Committee for the ISSCR Consortium on Advanced Stem Cell-Based Models in Drug Discovery and Development, about the need to accelerate the responsible integration of stem cell–derived models into preclinical drug development. Their conversation reflects growing regulatory and policy momentum around new approach methodologies (NAMs) and underscores the importance of rigorous standards, regulatory alignment, and cross-sector collaboration to improve reproducibility and advance more predictive, human-relevant therapies. Building on its long-standing leadership in global standards, ethics, and policy, the ISSCR is uniquely positioned to convene industry, academia, and regulators around this effort. The initiative also reflects the Society’s expanding industry engagement, with industry membership increasing nearly 180% over the past five years – creating new opportunities for strategic partnerships to address shared scientific and translational challenges. 2:35 | https://bit.ly/40lSK6l 12:55 | https://bit.ly/410bqbS 19:36 | https://bit.ly/40m2y06 26:21 | https://bit.ly/4bllTn2 32:53 | Guest Interview #ISSCR #NAMs #Organoids Subscribe today to never miss an episode! Listen on Apple: https://apple.co/2T8BhPA Listen on Spotify: https://spoti.fi/3xFdENP Official Website: https://stemcellpodcast.com/ Enjoy the other episodes in our full series playlist here: https://bit.ly/3HdhWzW Find the podcast on social media! Follow us on X: https://bit.ly/3pbfC65 Like us on Facebook: https://bit.ly/3LOu1Po Follow us on LinkedIn: https://bit.ly/3IeRCXb Follow us on Bluesky: https://bit.ly/4iNpWuJ This podcast is brought to you by STEMCELL Technologies! For a full list of products, as well as educational resources, visit our website: https://www.stemcell.com