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Watch the Full Video at https://www.jove.com/v/3252/video-rat.... Video-rate Scanning Confocal Microscopy and Microendoscopy - a 2 minute Preview of the Experimental Protocol Alexander J. Nichols, Conor L. Evans Harvard University , Program in Biophysics; Harvard-MIT, Division of Health Sciences and Technology; Harvard Medical School, Wellman Center for Photomedicine, Massachusetts General Hospital; The complete construction of a custom, real-time confocal scanning imaging system is described. This system, which can be readily used for video-rate microscopy and microendoscopy, allows for an array of imaging geometries and applications not accessible using standard commercial confocal systems, at a fraction of the cost. Visit https://www.jove.com?utm_source=youtu... to explore our entire library of 14,000+ videos of laboratory methods and science concepts. JoVE is the world-leading producer and provider of science videos with the mission to improve scientific research and education. Millions of scientists, educators, and students at 1500+ institutions worldwide, including schools like Harvard, MIT and Stanford benefit from using JoVE's extensive library of 14,000+ videos in their research,education and teaching. Subscribe to our channel: / jovejournalofvisualizedexperiments