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Does aspirin affect colon cancer risk? Kimmie Ng, MD, MPH, discusses the latest research in colon cancer prevention. This is an excerpt from a live video webchat on colon cancer prevention. Watch the full webchat video here: • Live Webchat: The Latest in Colon Cancer P... More information on colon cancer treatment and research: http://www.dana-farber.org/Adult-Care... Transcription: There is a lot of very strong evidence in support of a role for aspirin in preventing colon cancer. Unlike a lot the dietary and vitamin data that we’ve been talking about, there have actually been very good, well-designed, randomized clinical trials comparing aspirin to no aspirin in individuals who already have polyps and in people who have hereditary syndromes that lead to colon cancer, and these studies have shown that taking an aspirin can significantly reduce the risk of getting another polyp and of also developing cancer. So, in these high-risk individuals, aspirin does seem to have a role. And actually just this month, the United States Preventative Services Task Force came out with a recommendation that individuals ages 50 to 59 who have at least a 10% risk of developing cardiovascular disease over the next 10 years should be on a daily aspirin, both for prevention of heart attacks and strokes and other cardiovascular events, but also to prevent colon cancer.