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On October 15th, 2025, UHN was pleased to host a special seminar with Dr. Bali Pulendran, Professor of Pathology and of Microbiology & Immunology at Stanford University and a global leader in systems immunology and vaccinology. Dr. Pulendran is the Director of Stanford Medicine’s Institute for Immunity, Transplantation, and Infection. He received his undergraduate degree from the University of Cambridge, and his PhD from the Walter & Eliza Hall Institute in Melbourne, Australia. He then completed his postdoctoral work at Immunex Corporation in Seattle. His current work integrates multi-omics, computational modelling, and immune profiling to understand how innate immunity shapes adaptive responses to infection and vaccination. Dr. Pulendran has led the field in applying systems approaches to study immunity to infection and vaccination in humans. His notable work includes the discovery that dendritic cells (DCs), one of the key cell types orchestrating the immune response, comprise multiple functionally distinct subtypes. He also discovered the mechanisms by which microbial stimuli program DCs to modulate T-helper responses. His research has had a significant translational impact on vaccine design and immune monitoring, with publications in Nature, Science, Cell, and The New England Journal of Medicine. Thank you Dr. Pulendran for joining us and sharing this insightful work! #UHN #research #immunology #vaccineresearch #education #science