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caffeine and sodium benzoate

(coffeinum-natrii benzoas) A central nervous system stimulant. It works by stimulating the brain. It is used to restore mental alertness or wakefulness during fatigue or drowsiness. Caffeine (1,3,7-trimethylxanthine) is an alkaloid found naturally in foods and beverages such as coffee, tea, colas, and chocolate. The botanical sources include kola nuts, guarana, and yerba mate. It is also found in some headache and migraine medications, in certain dietary supplements used for weight loss, and in many energy drinks. (Indications) • cardiovascular weakness • stimulating the central nervous system when depressed • contagious and non-contagious diseases • respiratory depression • postpartum long-time lying • coronary, brain, and renal vessels spasms • reduced intestinal motor activity • muscle weakness (Side effects) • headache • excitement, agitation • anxiety, hyperventilation • shortness of breath • tachycardia, other cardiac arrhythmias • insomnia • increased diuresis • visual disturbances • nerve sensitivity (increased sensitivity to touch or pain) • tingling in the hands and feet • muscle tremors or twitches • tinnitus, hearing loss (Overdose) Overdose leads to irradiating of excitation. • vexation • motor excitation • anxiety • insomnia The induced caffeine effect is later transformed into inhibition, with reduced functional activity due to increased adrenaline secretion. • hyperglycemia • glycosuria • seisures • muscle trembling (Procedures in overdose) Early symptoms: • nausea, vomiting, tremor: Reduce the dose or discontinue the treatment. Serious conditions: • sinus bradycardia, seisures: Reduce the absorption of the drug (inducing vomiting, gastric lavage), water-electrolyte balance correction, administering laxatives. • excitation, seisures: Use narcotics (barbiturates). (Contraindications) • acute myodegeneration of the cardiac muscle • non-compensated valvular disease (Interaction) • With bromides in suitable doses: Balance the excitatory and inhibitory processes and cure neurosis and cortico-visceral diseases. • With hypnotics: The effects of hypnotics are weakened and caffeine enhances the effects of the nonsteroidal anti-inflammatory drugs (NSAIDs). Caffeine is an effective analgesic adjuvant because it increases the antinociceptive effect of NSAIDs while reducing the probability of side effects.