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http://www.arthritistreatmentcenter.com Switching TNF's can work for patients with psoriatic arthritis. Response has been very well when psoriatic arthritis patients switch TNFs. Nancy Walsh writing in MedPage Today reported ,"Most patients with psoriatic arthritis responded well to a first-line biologic, but for many of those who didn't initially respond, switching to another agent proved beneficial, a researcher reported" at the annual meeting of the British Society for Rheumatology. During "a retrospective survey that included 548 patients, 74% showed an adequate response to treatment with a tumor necrosis factor (TNF) inhibitor at 3 months, according to Meghna Jani, MBBS." Meanwhile, "among 94 patients who switched to a second TNF inhibitor, 52% responded 'very well,' she" said. Comment: It works for rheumatoid disease so this doesn't surprise me. • Biologic Therapy | Switching TNFs Can Work... 49%