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Biomechanical Weight-Bearing Prescription for Tibia diaphysis | ComeBack Mobility Case Study Description: In this case study, ComeBack Mobility presents a personalized biomechanical analysis for a 37-year-old Female patient with a Tibia diaphysis (AO Classification: 42-A1). 42-A1 42 – Fracture of the femoral shaft (diaphysis) A – Simple fracture type (one fracture line, two main fragments) 1 – Transverse fracture (fracture line runs perpendicular to the bone axis, angle greater than 30° from the long axis) Anatomical Location: The fracture is located in the diaphyseal (shaft) region of the femur — the long, central portion of the thigh bone between the proximal and distal metaphyses. Fracture Pattern: This is a transverse fracture, characterized by a straight, horizontal fracture line across the shaft of the femur. The bone is divided into two main fragments with no comminution or additional fracture lines. Using 3D segmentation of the bone fragments, fixator components, and fracture gap, we created a detailed finite element model to assess healing parameters. Based on the analysis of: • Fracture gap movement (mm) • Percentage of voxels in the Claes Healing Window • Fixation safety factor — we determined that the optimal weight-bearing range for this patient is 20%–40% of body weight. This range provides the best balance between stimulation for healing and structural safety, helping avoid complications such as delayed union or fixation failure.