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Biomarker Standardization: Quantifying Aging | Morgan Levine, Yale, Jamie Justice, Wake Forest скачать в хорошем качестве

Biomarker Standardization: Quantifying Aging | Morgan Levine, Yale, Jamie Justice, Wake Forest 4 года назад

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Biomarker Standardization: Quantifying Aging | Morgan Levine, Yale, Jamie Justice, Wake Forest
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Biomarker Standardization: Quantifying Aging | Morgan Levine, Yale, Jamie Justice, Wake Forest

Seminar summary: https://foresight.org/summary/biomark... Foresight Biotech & Health Extension Meeting sponsored by 100 Plus Capital 2021 program & apply to join: https://foresight.org/biotech-health-... Morgan Levine, Yale, Jamie Justice, Wake Forest Biomarker Standardization Morgan Levine, Yale University Morgan Levine is a ladder-rank Assistant Professor in the Department of Pathology at the Yale School of Medicine and a member of both the Yale Combined Program in Computational Biology and Bioinformatics, and the Yale Center for Research on Aging. Her work relies on an interdisciplinary approach, integrating theories and methods from statistical genetics, computational biology, and mathematical demography to develop biomarkers of aging for humans and animal models using high-dimensional omics data. As PI or co-Investigator on multiple NIH-, Foundation-, and University-funded projects, she has extensive experience using systems-level and machine learning approaches to track epigenetic, transcriptomic, and proteomic changes with aging and incorporate this information to develop measures of risk stratification for major chronic diseases, such as cancer and Alzheimer’s disease. Her work also involves development of systems-level outcome measures of aging, aimed at facilitating evaluation for geroprotective interventions. A number of the existing biological aging measures she has developed are being applied in both basic and observational research. Jamie Justice, Wake Forest School of Medicine Jamie Justice is an assistant professor in gerontology and geriatric medicine at the Wake Forest School of Medicine. She is a translational scientist conducting aging research, from basic biology of aging to clinical trials aimed at improving physical function and extending healthy lifespan (“healthspan”). She has taught undergraduate and graduate level courses, completed extensive training in biostatistics, managed several comparative aging studies and serve as PI and Co-I for clinical trials in older adults using repurposed pharmaceuticals, nutraceuticals, diet and lifestyle interventions. Zoom Transcription: https://otter.ai/u/ugIQ3G-fsTG-vl4Jk3... Find a written summary of this talk here (including slides, notes and more): https://foresight.org/salon/biomarker... Join us: ► Twitter:   / foresightinst   ► Facebook:   / foresightinst   ► Instagram:   / existentialhope   ► LinkedIn:   / foresight-institute   ► Support to join: https://foresight.org/donate/membership/ Foresight Institute advances technologies for the long-term future of life, focusing on molecular machine nanotechnology, biotechnology, and computer science. Follow us here for videos concerning our programs on Molecular Machines, Biotechnology & Health Extension, Intelligent Cooperation, and Existential Hope.

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