Heavy Metal Toxicities and Common Chelating Agents | Heavy Metal Poisoning Antidotes | GPAT | NIPER скачать в хорошем качестве

Heavy Metal Toxicities and Common Chelating Agents | Heavy Metal Poisoning Antidotes | GPAT | NIPER

Download the "Solution Pharmacy" Mobile App to Get All Uploaded Notes, Model Question Papers, Answer Papers, Online Tests and other GPAT Materials - https://play.google.com/store/apps/de... Textbook of Pharmacology by Bhandari Book Review Video -    • Text Book of Pharmacology By Prasan R  Bha...   Purchase Book from Amazon = https://amzn.to/3S0K68h Table of Content https://www.thieme.in/image/catalog/T... Sample Chapter of this book https://www.thieme.in/image/catalog/S... Heavy metal poisonings occur when toxic levels of certain heavy metals accumulate in the body, leading to adverse health effects. Common heavy metals involved in poisoning include lead, mercury, arsenic, cadmium, and thallium. Each heavy metal produces specific symptoms and targets different organs, such as the nervous system, kidneys, liver, and cardiovascular system. Antidotes are substances or treatments used to counteract the toxic effects of heavy metals and facilitate their elimination from the body. Here are some heavy metal poisonings and their respective antidotes: 1. Lead Poisoning: Lead poisoning is particularly concerning in children, where it can impair cognitive development and cause behavioral problems. The antidote for lead poisoning is dimercaptosuccinic acid (DMSA), also known as Succimer. DMSA is an oral chelating agent that binds to lead and helps its excretion through urine. 2. Mercury Poisoning: Mercury can damage the nervous system, kidneys, and other organs. For mercury poisoning, the antidotes are dimercaptosuccinic acid (DMSA) and dimercaprol (BAL). Both chelating agents form complexes with mercury, allowing its removal from the body. 3. Arsenic Poisoning: Arsenic exposure can cause skin lesions, cardiovascular problems, and an increased risk of certain cancers. The antidotes for arsenic poisoning include dimercaptosuccinic acid (DMSA) and dimercaprol (BAL), which help chelate arsenic and enhance its elimination. 4. Cadmium Poisoning: Cadmium primarily affects the kidneys and can lead to kidney damage and bone disorders. The chelating agent ethylenediaminetetraacetic acid (EDTA) is used as an antidote for cadmium poisoning. EDTA binds to cadmium and facilitates its excretion. 5. Thallium Poisoning: Thallium poisoning can lead to neurological and gastrointestinal symptoms. The antidote for thallium poisoning is Prussian blue (ferric hexacyanoferrate), which binds to thallium in the gastrointestinal tract, preventing its absorption and aiding in its elimination. 6. Iron Overload: Iron overload can occur due to excessive iron absorption or repeated blood transfusions. The antidote for iron overload is deferoxamine, a chelating agent that binds to excess iron and promotes its elimination. Get in touch with the solution by just clicking the following links- Facebook Group-   / solutionpharamcy   Mobile App - https://play.google.com/store/apps/de... New Channel (Pharmacy Dictionary)    / @pharmacydictionary   E-Mail for official and other work - solutionpharmacy@gmail.com #solutionpharmacy #Pharmacologyclass #Pharmacognosyvideos #GPAT