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In this episode, host Doreen Addrizzo-Harris, MD, FCCP, is joined by Amy Springer, MSN, FNP-C, to explore the challenges and treatment strategies for recalcitrant Mycobacterium avium complex (MAC) pulmonary disease, resistant MAC, and Mycobacterium abscessus (M abscessus) infections. They discuss diagnostic considerations, antibiotic resistance, treatment regimens—including US Food and Drug Administration-approved therapies and surgical options—and the critical role of patient compliance. This episode is part of CHEST’s Bridging Specialties®: Timely Diagnosis for NTM Disease and Bronchiectasis program. LEARN MORE » (https://www.chestnet.org/learning-and...) This program is produced in partnership with CHEST and is sponsored by Insmed Incorporated. Originally aired: July 1, 2025 HOST Doreen J. Addrizzo-Harris, MD, FCCP Fiona and Stanley Druckenmiller Professor of Pulmonary, Critical Care, and Sleep Medicine Director, NYULH Bronchiectasis and NTM Clinical and Translational Program NYU Grossman School of Medicine New York, NY PANELIST Amy Springer, MSN, FNP-C Senior Nurse Practitioner, NYULH Bronchiectasis and NTM Clinical and Translational Program Division of Pulmonary, Critical Care, and Sleep Medicine NYU Langone Health New York, NY