From Cohorts to Clinics: Dr. Sheng Fong on Clinical Aging Clocks & Longevity Medicine in Singapore скачать в хорошем качестве

From Cohorts to Clinics: Dr. Sheng Fong on Clinical Aging Clocks & Longevity Medicine in Singapore

Clinical aging clocks are moving from research cohorts into everyday healthcare — allowing doctors to measure and act on biological age, not just chronological age. At Longevity Summit Dublin 2025, Dr. Sheng Fong (Consultant Geriatrician & Clinician Scientist, Ng Teng Fong General Hospital, Singapore) presents how clinical aging clocks are moving from research cohorts into real-world healthcare. Drawing on one of Asia’s largest population-based cohorts — the Singapore Chinese Health Study and the pioneering LinAge2 clock, Dr. Fong shares: Why Singapore is becoming a longevity hotspot and how prevention is being embedded into national health policy. How aging clocks predict mortality, healthspan, and resilience more accurately than conventional clinical risk scores. Real patient cases from the CogAge pilot study showing how clocks detect hidden disease, nutritional deficiencies, and early dementia risk. The vision for personalized intervention targeting and tracking how lifestyle or therapeutics can slow biological aging. How large-scale longitudinal health records and AI platforms will drive the next frontier of clinical longevity medicine. This talk bridges cutting-edge research and frontline geriatrics, offering a glimpse into how doctors may soon use aging clocks as everyday clinical tools. Filmed at Longevity Summit Dublin 2025. Dr. Fong is based in Singapore, working at Ng Teng Fong General Hospital. Alis https://www.alishealth.ai/ Ng Teng Fong General Hospital https://www.ntfgh.com.sg/ Chapters 00:00 – Introduction & Singapore’s healthcare system 02:00 – National prevention program: Healthier SG 04:00 – AI, precision medicine & aging clocks 06:00 – LinAge2 clock: predicting biological age, mortality & healthspan 08:00 – Case studies from the CogAge pilot (hidden disease, dementia, stroke risk) 13:00 – Why clocks must be interpretable & actionable 17:00 – Clinical examples: dementia progression, CRP, cardiometabolic drivers 21:00 – Personalized interventions & treatment targeting 25:00 – Tracking intervention efficacy (calorie restriction, lifestyle) 27:00 – Singapore Chinese Health Study & SG70 cohort 30:00 – National AI platform & future of clinical aging clocks 32:00 – Final reflections & Q&A #LongevitySummitDublin #LSD25 #AgingClocks #BiologicalAge #LongevityMedicine #PrecisionMedicine #HealthyLongevity #Geriatrics #AIisHealthcare #SingaporeHealthcare #HealthierSG #SingaporeLongevity