Searching the PDB for High-Quality Ligand-Bound Structures скачать в хорошем качестве

Searching the PDB for High-Quality Ligand-Bound Structures

High-quality ligand-bound structures are indispensable for understanding the interaction between small molecule ligands and their target proteins and nucleic acids. In this webinar, we illustrate the PDB ligand validation and annotation process, and explain the metrics that measure ligand quality from various perspectives. Learn how to search the PDB for high-quality ligand-bound structures using these metrics via RCSB.org and RCSB PDB APIs. Additional resources for this webinar are available at https://pdb101.rcsb.org/train/trainin... Video sections: 00:00 Introduction 01:11 Ligand Data in the PDB 12:19 Ligand Validation at the PDB 21:43 Ligand Quality Comparison within the PDB 31:28 Search PDB for Ligand Structures of Better Quality 32:32 Demonstration: Searching for ligands of better quality using RCSB.org and RCSB PDB APIs