Biohacking Resilience: Engineering the Human System with Marcelo Garcia скачать в хорошем качестве

Biohacking Resilience: Engineering the Human System with Marcelo Garcia

Biohacking isn’t just supplements and gadgets. It’s about stress-testing the most complex system you’ll ever operate: your own body. We’re kicking off the third season of Nerding Out with Viktor with a deep dive into extreme biohacking. Viktor is joined by Marcelo Garcia, who recently completed a 50-day water-only fast while hiking nearly 1,000km, capturing extensive biometric data across DEXA scans, VO2 max testing, HRV, metabolic panels, and continuous glucose monitoring. This episode focuses on biohacking through a systems lens. Not trends. Not shortcuts. Controlled load. Measured adaptation. Clear feedback loops. Marcelo treats human physiology the way engineers treat production systems: introduce stress, observe response, identify constraints, and optimize for resilience. The result is a data-backed exploration of fat oxidation limits, muscle preservation under scarcity, immune regeneration, and biological age modeling. For technically inclined builders, this is biohacking grounded in systems thinking. In this episode, we cover: *What actually happens during a 50-day water fast *Maximum fat oxidation and how muscle can be preserved *Why movement during fasting changes metabolic outcomes *Cold exposure as hormesis and resilience training *Biological age vs chronological age and how to measure it *Using AI to analyze 100+ biomarkers for health span projections *Endogenous biohacking vs supplement-driven optimization Marcelo’s core idea is simple: Modern life removed stress. Biology still expects it. As we start 2026, this episode asks a practical question: Have you stress-tested your own operating system? Timestamps 00:00 - Kicking Off 2026: Why we’re starting the year with biohacking 07:30 - Systems Thinking Applied to the Human Body: From infrastructure engineering to physiology 18:30 - The Explorer Mindset: Why push biological limits 28:30 - The 50-Day Fast: Design, constraints, and execution 34:45 - The Metabolic Deep Dive: Ketosis, autophagy, gluconeogenesis, fat oxidation 39:40 - Movement as Signal: How hiking preserved muscle mass 45:50 - Measuring Biological Age: VO2 max, HRV, metabolic age, PhenoAge 53:00 - Cognitive Performance Under Scarcity: Productivity during prolonged fasting 59:10 - Hormesis & Resilience Engineering: Why discomfort drives adaptation 1:04:00 - What’s Next: Everest Base Camp and future experiments 1:08:30 - AI & Longevity Modeling: Using GPT to project healthspan