Yang Feng, PhD, discusses скачать в хорошем качестве

Yang Feng, PhD, discusses

Recorded at the 67th American Society of Hematology Annual Meeting and Exposition, Yang Feng, PhD, discusses her ASH abstract titled (No.631) “Targeting DOCK1 to prevent clonal expansion of TP53-mutant clonal hematopoiesis under genotoxic stress.” Dr. Feng, postdoctoral scholar at Stanford's Institute of Stem Cell Biology and Regenerative Medicine and lead author on the abstract, provides an overview of the study in this video. The investigators developed a human model of TP53-mutant clonal hematopoiesis that expands under genotoxic therapies, then identified DOCK1 inhibition as a strategy to block this expansion and prevent therapy-related myeloid neoplasms. Reference Feng Y, Koehnke T, Patrick B. Inhibition of DOCK1 prevents the clonal expansion of high-risk TP53-mutant clonal hematopoiesis induced by genotoxic stressors. Abstract #631. Presented at the 67th American Society of Hematology Annual Meeting and Exposition. December 6–9; Orlando, Florida.